About the three -dimensional organ on a chip
Scientists have created a three-dimensional (3D) organ-on-a-chip that can mimic the heart’s amazing biomechanical properties and could help in studying cardiac diseases, screening and development of drugs. The unique aspect of the new device is that it controls the mechanical force applied to cardiac cells. This allows the researchers to reproduce the mechanical conditions of the living heart, which is continually stretching and contracting, in addition to its electrical and biochemical environment.
Possible benefits of the device
1. It could prove invaluable in studying cardiac diseases, drug screening and drug development, and, in the future, in personalised medicine by identifying the cells taken from patients that can be used to patch damaged hearts effectively.
2. The device faithfully reproduces the response of cardiac cells to two different drugs that affect heart function in humans.